How sticky are our proteins? Quantifying hydrophobicity of the human proteome
We are happy to share our recent publication by Juami Hermine Mariama van Gils, Dea Gogishvili, Jan van Eck, Robbin Bouwmeester, Erik van Dijk, and Sanne Abeln. Check out the ISMB-ECCB talk by Juami van Gils and Dea Gogishvili on our YouTube channel. Abstract: Proteins tend to bury hydrophobic residues inside their core during the folding process to provide stability to the protein structure and to prevent aggregation. Nevertheless, proteins do expose some ‘sticky’ hydrophobic residues to the solvent. These residues can play an important functional…